Post tags: | atherosclerosis | heart_health | slimjohn | REGRESSION - How I did it! » Arteries Are Better Today Than 9 Years Ago!! - by slimjohn ADVANCED TOPICS » YOUR Lab & Test Results: Feedback » Advice Needed on Latest Scan by LVL

I highly recommend that you take sufficient vitamin D3, vitamin A, and vitamin K complex with a lot of MK-7 to prevent calcification.

Good on the homocysteine decrease!

Try taking pure niacin (nicotinic acid); start at low dose and work up. I used to take Slo-Niacin and pure niacin flush is not any different. Take after a meal and drink plenty of fluid.

Also, consider taking aged garlic with the fish oil. There is a synergistic effect. See my post on this thread: “Fish Oil still good??” I take 2 capsules 2x daily of Kyolic Aged Garlic Extract Extra Strength RESERVE Cardiovascular ( carries this). Each capsule is 600mg. See this thread “Aged Garlic Reverses Soft Plaque by 80% in New Study.”

slimjohn on kyolic garlic

Thanks for the update! Well, that article – apparently his organization released it to PR news organization – should have been reviewed before release. Makes me wonder how anyone, particularly those in research, can accidentally confuse 1200mg with 2400mg. Not only that, but there has been no correction AFAIK. Dr. Budoff made a presentation at the 9th annual scientific meeting of the Society of Cardiovascular Computed Tomography to be held July 10-13, 2014 in San Diego, California. I’ve not see anything on the study in print.

Nevertheless, I will stay with the 2400 mg AGE and evaluate throughout the remainder of the year (some things take longer to show consistent benefits). The PR news mistake may be the best unintentional benefit. :-) As with most substances, the rate of benefit effects decline with dosage so 2x dosage does not necessarily mean 2x benefit outcomes. Anything above 1x is okay with me. LOL

Regardless, this is one substance where being aggressive may just be optimal at least beyond the plaque reduction. It reduces vascular smooth muscle proliferation, decreases oxLDL, increases eNOS and NO (endothelial function), and naturally increases the endogenous antioxidants glutathione, glutathione reductase, and SOD (superoxide dismutase), improves lipids via reduction of HMG COA reductase (similar to statins) to reduce total cholesterol and triglycerides. I especially like natural induced increase in endogenous antioxidants. It also increases activation of AMPK so all good to me.

Linda - LCL: I've had similar huge swings in LDL-P and I've got Lp(a) as well. Dr. D has mentioned several times that some folks, especially those with Lp(a) are very sensitive to carbohydrate indulgences, such that they can cause huge increases in small particles and take weeks to wear off. I'm kind of thinking that's what it might be.

The H Factor Solution: Homocysteine, the Best Single Indicator of Whether You Are Likely to Live Long or Die Young. authors: James Braly M.D., Patrick Holford, Jonathan Wright M.D.

slimjohn on homocysteine
Following the guidelines of The H Factor Solution should reduce homocysteine. However, for some, getting to 6 may not be so easy. While the authors offer suggestions on diet and supplements, keep in mind that one's mileage may differ and they may be insufficient. For example, folic acid may work for some people but for most 5-MTHR (methlyfolate) is superior. Some people may require higher dosages methylfolate than recommended (I do!). They mention TMG (TMG converts homocysteine back to methionine) but note that they state that for some people much higher dosages may be required. If you are sensitive to too much methyl groups/TMG you may experience side effects (fatigue, nausea, hair loss, dizziness, spaciness). So, it may be best at some time to consider optimizing methylation and to know how the various B vitamins effect certain polymorphisms. Since methylation is a big, critical part of reducing homocysteine, it may be best to get 23andme genetic data to see what specifically may need addressing to optimize methylation. Make the adjustments and follow up with methylation panel to confirm. For example, I have COMT polymorphism that processes methyl groups slowly. I take niacin that consumed methyl groups and seems to offset COMT effects. That's a double benefit. I've had to make adjustments after adding TMG which seems to work directly within the methionione cycle and does not effect COMT (I've not noticed). I added TMG about 3 months ago and am holding off to get a ton of labs next months so the results will tell me how the protocol is working. Purchase the book. There's more to the protocol than just supplements. :-) GENERAL TOPICS » Strategies: Prevention, Mitigation of CVD » Plaque Stability & Plaque Regression - by slimjohn

The combination of niacin plus simvastatin reduces TAV (total atheroma volume) and PAV (percent atheroma volume), decreases coronary plaque volume and attenuates the inflammatory response in patients with intermediate coronary artery stenosis. See full article: The Effects of Statin and Niacin on Plaque Stability, Plaque Regression, Inflammation and Oxidative Stress in Patients With Mild to Moderate Coronary Artery Stenosis Slimjohn's Supplement and Products List (75% coronary artery regression, 2007-2016) - ADVANCED TOPICS » Cell & Mitochondria Health New Energy Plus! by slimjohn

I take early morning and late evenings: by slimjohn

Early Morning -

  • 1 each - Life Extension Super K with Advanced K2 Complex
  • 1 each - Vitacost Vitamin K2 (MK-7) with Nattokinase

Late Evening -

  • 1 each - Life Extension Super K with Advanced K2 Complex
  • 1 each - Vitacost Vitamin K2 (MK-7) with Nattokinase

Vitacost Vitamin K Complex

  • Vitamin K2 (as menaquinone-7) 200 mcg
  • Vitamin K1 (phyloquinne) 200 mcg

Vitacost Vitamin K2 (MK-7) with Nattokinase

  • MK-7 (Vitamin K2 as Menaquinone-7) 100 mcg
  • Nattokinase (from Natto Extract) 320 FU (Fibrin Units)

I take both mornings and evenings (for a couple of years now) to ensure I have 24 hour coverage. Does it work? Who knows? I will get CAC scan soon so that may give some indication if arterial inflammation has slowed expanding surfaces for possible calcification. What I do know is that it is better to have sufficient Ks than insufficient Ks with reduced level carboxylation of matrix GLA which makes for an arterial wall primer for calcification.

I also ensure that I get plenty of magnesium (Natural Calm, 600mg- 900mg) that inhibits the calcification (phosphate binding) chemistry. It all depends on the level of D3 (which varies over the day & night). Vitamin A (retinol) does prevent excessive level of D3 (A is antagonist of D3; visa versa). Note: Vitamin K is needed to help the body make blood clots; people taking anti-coagulant and anti-platelet medication should consult their doctor before adding Vitamin K to their daily regimen.

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